Each weekly issue of Intestinal Cell News features a current, relevant review article to help keep our readers informed on the overarching trends and milestones in the intestinal cell biology field. On this page, you can find each of these archived review articles searchable by title, journal and date. You can also submit a review paper to our editors to be considered for the next issue of Intestinal Cell News.
Title   Journal   Publication Date   Newsletter Issue  
The DNA Damage Response Pathway as a Land of Therapeutic Opportunities for Colorectal Cancer
Mauri, G; Arena, S; Siena, S; Bardelli, A; Satore-Bianchi, A
Ann Oncol 2020-06-12 6.21 | Jun 12
Patient-Derived In Vitro Models for Drug Discovery in Colorectal Carcinoma
Ramzy, G; Koessler, T; Ducrey, E; McKee, T; Ris, F; Buchs, N; Brandt, L; Dietrich, P; Sliwinska, P
Cancers 2020-05-31 6.20 | Jun 5
Targeting Protein Synthesis in Colorectal Cancer
Schmidt, S; Denk, S; Wiegering, A
Cancers 2020-05-29 6.19 | May 29
Targeting Desmosomal Adhesion and Signaling for Intestinal Barrier Stabilization in Inflammatory Bowel Diseases—Lessons from Experimental Models and Patients
Shlegel, N; Borner, K; Waschke, J
Acta Physiol (Oxf) 2020-05-18 6.18 | May 22
Organoids and Bioengineered Intestinal Models: Potential Solutions to the Cryptosporidium Culturing Dilemma
Gunasekera, S; Zahedi, A; Dea, M; King, B; Monis, P; Thierry, B; Carr, JM; Ryan, U
Microorganisms 2020-05-11 6.17 | May 15
Interleukin-22 and Intestinal Homeostasis: Protective or Destructive?
Shohan, M; Dehghani, R; Khodadadi, A; Dehnavi, S; Ahmadi, R; Joudaki, N; Houshmandfar, S; Shamshiri, M; Shojapourian, S; Bagheri, N
IUBMB Life 2020-05-04 6.16 | May 8
The Nano-Intestine Interaction: Understanding the Location-Oriented Effects of Engineered Nanomaterials in the Intestine
Cui, X; Bao, L; Wang, X; Chen, C
Small 2020-04-29 6.15 | May 1
Cystic Fibrosis, CFTR, and Colorectal Cancer
Scott, P; Anderson, K; Singhania, M; Cormier, R
Int J Mol Sci 2020-04-21 6.14 | Apr 24
Head-to-Head Trials in Inflammatory Bowel Disease: Past, Present and Future
Poullion, L; Travis, S; Bossuyt, P; Danese, S; Peyrin-Biroulet, L
Nat Rev Gastroenterol Hepatol 2020-04-17 6.13 | Apr 17
Single-Cell Protein and RNA Expression Analysis of Mononuclear Phagocytes in Intestinal Mucosa and Mesenteric Lymph Nodes of Ulcerative Colitis and Crohn’s Disease Patients
Chapuy, L; Sarfati, M
Cells 2020-03-27 6.12 | Apr 3
Stem Cell Signaling Pathways in the Small Intestine
Takahashi, T; Shiraishi, A
Int J Mol Sci 2020-03-16 6.11 | Mar 27
Innate Lymphoid Cell-Epithelial Cell Modules Sustain Intestinal Homeostasis
Diefenbach, A; Gnafakis, S; Shomrat, O
Immunity 2020-03-17 6.10 | Mar 20
JAK-STAT Pathway Targeting for the Treatment of Inflammatory Bowel Disease
Salas, A; Hernandez-Rocha, C; Duijvestein, M; Faubion, W; McGovern, D; Vermiere, S; Vetrano, S; Casteele, NV
Nat Rev Gastroenterol Hepatol 2020-03-19 6.10 | Mar 20
Intestinal Organoids: A Tool for Modeling Diet-Microbiome-Host Interactions
Rupert, J; Schweiger, PJ; Mattivi, F; Tuohy, K; Jensen, KB; Lunardi, A
Trends Endocrinol Metab 2020-03-09 6.09 | Mar 13
Metabolic and Immunologic Control of Intestinal Cell Function by mTOR
Fritsch, SD; Weichhart, T
Int Immunol 2020-03-06 6.08 | Mar 6
Pathway Paradigms Revealed from the Genetics of Inflammatory Bowel Disease
Graham, DB; Xavier, RJ
Nature 2020-02-26 6.07 | Feb 28
Organoid Models of Gastrointestinal Cancers in Basic and Translational Research
Lau, HCH; Kranenburg, O; Xiao, H; Yu, J
Nat Rev Gastroenterol Hepatol 2020-02-25 6.07 | Feb 28
Epithelial Toll-Like Receptors and Their Role in Gut Homeostasis and Disease
Burgueno, JF; Abreu, MT
Nat Rev Gastroenterol Hepatol 2020-02-26 6.07 | Feb 28
Gastrointestinal Tract Modeling Using Organoids Engineered with Cellular and Microbiota Niches
Min, S; Kim, S; Cho, SW
Exp Mol Med 2020-02-26 6.07 | Feb 28
Crosstalk among Colon Cancer-Derived Exosomes, Fibroblast-Derived Exosomes, and Macrophage Phenotypes in Colon Cancer Metastasis
Wang, M; Su, Z; Barnie, P
Int Immunopharmacol 2020-02-11 6.06 | Feb 21
How Do Immune and Mesenchymal Cells Influence the Intestinal Epithelial Cell Compartment in Inflammatory Bowel Disease? Let’s Crosstalk About It!
Rees, WD; Sly, LM; Steiner, TS
J Leukoc Biol 2020-02-14 6.05 | Feb 14
Roles of nAChR and Wnt Signaling in Intestinal Stem Cell Function and Inflammation
Takahashi, T
Int Immunopharmacol 2020-01-30 6.04 | Feb 7
Microbial Metabolites & Intestinal Stem Cells Tune Intestinal Homeostasis
Xing, PY; Pettersson, S; Kundu, P
Proteomics 2020-01-29 6.03 | Jan 31
Opioids in Cancer Development, Progression and Metastasis: Focus on Colorectal Cancer
Szczepaniak, A; Fichna, J; Zielinska, M
Curr Treat Options Oncol 2020-01-22 6.02 | Jan 24
Intestinal Organoids as a Tool for Inflammatory Bowel Disease Research
Angus, HCK; Butt, AG; Schultz, M; Kemp, RA
Front Med 2020-01-17 6.01 | Jan 17
Epigenetics/Epigenomics and Prevention by Curcumin of Early Stages of Inflammatory‐Driven Colon Cancer
Wu, R; Wang, L; Yin, R; Hudlikar, R; Li, S; Kuo, HCD; Peter, R; Sargsyan, D; Guo, Y; Liu, X; Kong, ANT
Mol Carcinog 2019-12-09 5.48 | Dec 20
Establishing Boundaries: The Relationship That Exists Between Intestinal Epithelial Cells and Gut-Dwelling Bacteria
Callaghan, A.; Corr, S.
Microorganisms 2019-12-09 5.47 | Dec 13
Molecular Anatomy and Pathogenic Actions of Helicobacter pylori CagA That Underpin Gastric Carcinogenesis Takahashi-Kanemitsu, A.; Knight, C.; Hatakeyama, M. Cell Mol Immunol 2019-12-05 5.46 | Dec 6
Vitamin D and the Nutritional Environment in Functions of Intestinal Stem Cells: Implications for Tumorigenesis and Prevention Li, W.; Peregrina, K.; Houston, M.; Augenlicht, L. J Steroid Biochem Mol Biol 2019-11-26 5.46 | Dec 6
Intestinal Organoids for Cystic Fibrosis Research de Poel, E.; Lefferts, J.; Beekman, J. J Cyst Fibros 2019-11-28 5.46 | Dec 6
Role of Environmental Factors in the Pathogenesis of Crohn’s Disease: A Critical Review Chen, Y.; Wang, Y.; Shen, J. Int J Colorectal Dis 2019-11-16 5.45 | Nov 29
New Addiction to the NRF2-Related Factor NRF3 in Cancer Cells: Ubiquitin-Independent Proteolysis via the 20S Proteasome Kobayashi, A.; Waku, T. Cancer Sci 2019-11-19 5.44 | Nov 22
Long Noncoding RNA (lncRNA)-Mediated Competing Endogenous RNA Networks Provide Novel Potential Biomarkers and Therapeutic Targets for Colorectal Cancer Wang, L.; Cho, K.; Li, Y.; Tao, G.; Xie, Z.; Guo, B. Int J Mol Sci 2019-11-16 5.44 | Nov 22
Wnt Signaling in 3D: Recent Advances in the Applications of Intestinal Organoids Merenda, A.; Fenderico, N.; Maurice, M. Trends Cell Biol 2019-11-09 5.43 | Nov 15
Molecular Mechanisms of Curcumin and Its Analogs in Colon Cancer Prevention and Treatment Thilgavathi, R.; Selvam, C.; Prabu, L.; Jordan, B.; Purushothaman, Y.; Et al. Life Sci 2019-11-06 5.43 | Nov 15
Serrated Colorectal Cancer: The Road Less Traveled? Nakanishi, Y.; Diaz-Meco, M.; Moscat, J. Trends Cancer 2019-10-28 5.42 | Nov 8
Serrated Colorectal Cancer: The Road Less Traveled? Nakanishi, Y; Diaz-Meco, MT; Moscat, J Trends Cancer 2019-01-28 5.41 | Nov 1
Immune Checkpoint Inhibitors for the Treatment of MSI-H/MMR-D Colorectal Cancer and a Perspective on Resistance Mechanisms Sahin, I.; Akce, M.; Alese, O.; Shaib, W.; Lesinski, G.; Et al. Br J Cancer 2019-10-14 5.40 | Oct 25
Human Colorectal Cancer From the Perspective of Mouse Models Stastna, M.; Janeckova, L.; Hrckulak, D.; Kriz, V.; Korinek, V. Genes (Basel) 2019-10-11 5.40 | Oct 25
BMP Signaling in Development, Stem Cells, and Diseases of the Gastrointestinal Tract Zhang, Y.; Que, J. Annu Rev Physiol 2019-10-16 5.39 | Oct 18
Starch Digestion by Gut Bacteria: Crowdsourcing for Carbs Cerqueira, F.; Photenhauer, A.; Pollet, R.; Brown, H.; Koropatkin, N. Trends Microbiol 2019-10-14 5.39 | Oct 18
Chronic Stress, Inflammation, and Colon Cancer: A CRH System-Driven Molecular Crosstalk Baritaki, S.; de Bree, E.; Chatzaki, E.; Pothoulakis, C. J Clin Med 2019-10-12 5.39 | Oct 18
Opinion: Are Organoids the End of Model Evolution for Studying Host Intestinal Epithelium/Microbe Interactions? George, M.; Rahman, M.; Connors, J.; Stadnyk, A. Microorganisms 2019-09-29 5.38 | Oct 11
Diet, Microbiota and Colorectal Cancer Grazioso, T.; Brandt, M.; Djouder, N. iScience 2019-10-10 5.38 | Oct 11
Omega Fatty Acids and Inflammatory Bowel Diseases: An Overview Marton, L.; Goulart, R.; Carvalho, A.; Barbalho, S. Int J Mol Sci 2019-09-30 5.37 | Oct 4
Adhesion Mechanisms of Lactic Acid Bacteria: Conventional and Novel Approaches for Testing Alp, D.; Kuleasan, H. World J Microbiol Biotechnol 2019-10-01 5.37 | Oct 4
Gut Microbiota in Colorectal Cancer: Mechanisms of Action and Clinical Applications Wong, S.; Yu, J. Nat Rev Gastroenterol Hepatol 2019-09-25 5.36 | Sep 27
Microsatellite Instability and Immune Checkpoint Inhibitors: Toward Precision Medicine against Gastrointestinal and Hepatobiliary Cancers Eso, Y.; Shimizu, T.; Takeda, H.; Takai, A.; Marusawa, H. J Gastroenterol 2019-09-07 5.35 | Sep 20
Microsatellite Instability and Immune Checkpoint Inhibitors: Toward Precision Medicine against Gastrointestinal and Hepatobiliary Cancers Eso, Y.; Shimizu, T.; Takeda, H.; Takai, A.; Marusawa, H. J Gastroenterol 2019-09-07 5.34 | Sep 12
The Role of Adaptor Protein CARD9 in Colitis-Associated Cancer Zhong, X; Chen, B; Liu, M; Yang, Z Mol Ther Oncolytics 2019-08-30 5.33 | Sep 6
Development and Evolution of Gut Structures: From Molecules to Function Annuziata, R.; Andrikou, C.; Perillo, M.; Cuomo, C.; Arnone, M. Cell Tissue Res 2019-08-24 5.32 | Aug 30
Multitasking Kinase RIPK1 Regulates Cell Death and Inflammation Newton, K. Cold Spring Harb Perspect Biol 2019-08-19 5.31 | Aug 23
Influence of Growth Hormone and Glutamine on Intestinal Stem Cells: A Narrative Review Chen, Y.; Tsai, Y.; Tseng, B.; Tseng, S. Nutrients 2019-08-17 5.31 | Aug 23
Epigenetic Biomarkers in Colorectal Cancer Patients Receiving Adjuvant or Neoadjuvant Therapy: A Systematic Review of Epidemiological Studies Barchitta, M.; Maugeri, A.; Li Destri, G.; Basile, G.; Agodi, A. Int J Mol Sci 2019-08-06 5.30 | Aug 16
Epigenetic Biomarkers in Colorectal Cancer Patients Receiving Adjuvant or Neoadjuvant Therapy: A Systematic Review of Epidemiological Studies Barchitta, M.; Maugeri, A.; Li Destri, G.; Basile, G.; Agodi, A. Int J Mol Sci 2019-08-06 5.29 | Aug 9
Intestinal Epithelial Barrier Functions in Aging Branca, J.; Gulisano, J.; Nicoletti, C. Ageing Res Rev 2019-07-29 5.28 | Aug 2
Exploring the Best Treatment Options for BRAF-Mutant Metastatic Colon Cancer Taieb, J.; Lapeyre-Prost, A.; Puig, P.; Zaanan, A. Br J Cancer 2019-07-29 5.28 | Aug 2
Innate Immune Cell-Epithelial Crosstalk during Wound Repair Brazil, J.; Quiros, M.; Nusrat, A.; Parkos, C. J Clin Invest 2019-07-22 5.27 | Jul 26
Biomarker-Guided Therapy for Colorectal Cancer: Strength in Complexity Sveen, A.; Kopetz, S.; Lothe, R. Nat Rev Clin Oncol 2019-07-09 5.25 | Jul 12
Canonical and Non-Canonical Inflammasomes in Intestinal Epithelial Cells Winsor, N.; Krustev, C.; Bruce, J.; Philpott, D.; Girardin, S. Cell Microbiol 2019-07-02 5.24 | Jul 5
The Role of Adipose Tissue in the Pathogenesis and Therapeutic Outcomes of Inflammatory Bowel Disease Eder, P.; Adler, M.; Dobrowolska, A.; Kamhieh-Milz, J.; Witowski, J. Cells 2019-06-21 5.24 | Jul 5
Targeting Immune Cell Circuits and Trafficking in Inflammatory Bowel Disease Neurath, M. Nat Immunol 2019-06-24 5.23 | Jun 28
Nobiletin and Derivatives: Functional Compounds from Citrus Fruit Peel for Colon Cancer Chemoprevention Goh, J.; Tan, L.; Goh, J.; Chan, K.; Pusparajah, P.; Et al. Cancers 2019-06-21 5.23 | Jun 28
Mini-Gut: A Promising Model for Drug Development Yin, Y.; de Jonge, H.; Wu, X.; Yin, Y. Drug Discov Today 2019-06-15 5.22 | Jun 21
Gut Organoids: Mini-Tissues in Culture to Study Intestinal Physiology and Disease Almeqdadi, M.; Mana, M.; Roper, J.; Yilmaz, Ö. Am J Physiol Cell Physiol 2019-06-19 5.22 | Jun 21
Fecal Microbiota Transplantation as a New Therapy: From Clostridioides Difficile Infection to Inflammatory Bowel Disease, Irritable Bowel Syndrome, and Colon Cancer Borody, T.; Eslick, G.; Clancy, R. Curr Opin Pharmacol 2019-06-05 5.21 | Jun 14
Capturing the Biologic Onset of Inflammatory Bowel Diseases: Impact on Translational and Clinical Science Sorrentino, D.; Nguyen, V.; Chitnavis, M. Cells 2019-06-06 5.21 | Jun 14
The Anti-Inflammatory Effects of Dietary Anthocyanins against Ulcerative Colitis Li, S.; Wu, B.; Fu, W.; Reddivari, L. Int J Mol Sci 2019-05-27 5.20 | Jun 7
Metabolic Pathways Regulating Colorectal Cancer Initiation and Progression Vecchia, S.; Sebastián, C. Semin Cell Dev Biol 2019-05-28 5.19 | May 31
The Potential Therapeutic and Prognostic Impacts of the C-MET/HGF Signaling Pathway in Colorectal Cancer Parizadeh, S.; Jafarzadeh-Esfehani, R.; Fazilat-Panah, D.; Hassanian, S.; Shahidsales, S.; Et al. IUBMB Life 2019-05-22 5.19 | May 31
Emerging Roles of C-Myc in Cancer Stem Cell-Related Signaling and Resistance to Cancer Chemotherapy: A Potential Therapeutic Target against Colorectal Cancer Elbadawy, M.; Usui, T.; Yamawaki, H.; Sasaki, K. Int J Mol Sci 2019-05-11 5.18 | May 24
Vitamin A and Vitamin D Regulate the Microbial Complexity, Barrier Function, and the Mucosal Immune Responses to Ensure Intestinal Homeostasis Cantorna, M. Crit Rev Biochem Mol Biol 2019-05-14 5.17 | May 17
An Update on the Morphology and Molecular Pathology of Serrated Colorectal Polyps and Associated Carcinomas Pai, R.; Bettington, M.; Srivastava, A.; Rosty, C. Mod Pathol 2019-04-25 5.15 | May 3
The Role of Autophagy in Maintaining Intestinal Mucosal Barrier Wu, Y.; Tang, L.; Wang, B.; Sun, Q.; Zhao, P.; Li, W. J Cell Physiol 2019-05-24 5.15 | May 3
Emerging Roles of Bile Acids in Mucosal Immunity and Inflammation Chen, M.; Takeda, K.; Sundrud, M. Mucosal Immunol 2019-04-05 5.13 | Apr 12
Mucus and Mucins in Diseases of the Intestinal and Respiratory Tracts Hannson, G. J Intern Med 2019-04-08 5.13 | Apr 12
Cytokine Networks in the Pathophysiology of Inflammatory Bowel Disease Friedrich, M.; Pohin, M.; Powrie, F. Immunity 2019-04-26 5.14 | Apr 26
The IL-23/IL-17 Pathway in Human Chronic Inflammatory Diseases—New Insight from Genetics and Targeted Therapies Rogge, L.; Bianchi, E. Genes Immun 2019-04-19 5.14 | Apr 26
The Gut and the Inflammatory Bowel Diseases Inside-Out: The Extra-Intestinal Manifestations Ribadone, D.; Pellicano, R.; Actis, G. Minerva Gastroenterol Dietol. 2019-04-16 5.14 | Apr 26
ILC3 Function as a Double-Edged Sword in Inflammatory Bowel Diseases Zeng, B.; Shi, S.; Ashworth, G.; Dong, C.; Liu, J.; Zing, F. Cell Death Dis 2019-04-08 5.13 | Apr 12
Pharmacological Autophagy Regulators as Therapeutic Agents for Inflammatory Bowel Diseases Retnakumar, S; Muller, S Trends Mol Med 2019-04-02 5.12 | Apr 5
Stem Cells in Homeostasis and Cancer of the Gut Heijden, M; Vermeulen, L Mol Cancer 2019-03-30 5.12 | Apr 5
Harnessing the Innate Immune System and Local Immunological Microenvironment to Treat Colorectal Cancer Kather, J; Halama, N Br J Cancer 2019-04-02 5.12 | Apr 5
Targeting siRNA in Colorectal Cancer Therapy: Nanotechnology Comes into View Aghamiri, S; Jafarpour, A; Malekshahi, Z; Gomari, M; Negahdari, B J Cell Physiol 2019-03-28 5.11 | Mar 29
Immunotherapy in Colorectal Cancer: Rationale, Challenges and Potential Ganesh, K; Stadler, Z; Cercek, A; Mendelsohn, R; Shia, J; Segal, N; Diaz Jr, L Nat Rev Gastroenterol Hepatol 2019-03-18 5.10 | Mar 22
Bioengineering and Regeneration of Gastrointestinal Tissue: Where Are We Now and What Comes Next? Zakhem, E; Raghavan, S; Bitar, K; Suhar, R Expert Opin Biol Ther 2019-03-16 5.10 | Mar 22
Exploiting the Message from Cancer: The Diagnostic Value of Extracellular Vesicles for Clinical Applications Kosaka, N; Kogure, A; Ochiya, T; et al Exp Mol Med 2019-03-15 5.09 | Mar 15
Systems Biology Approaches to Investigating the Roles of Extracellular Vesicles in Human Diseases Gezsi, A; Kovacs, A; Visnovitz, T; Buzas, E Exp Mol Med 2019-03-15 5.09 | Mar 15
The Role of Interleukin-13 in Chronic Inflammatory Intestinal Disorders Giuffirda, P; Caprioli, F; Facciotti, F; Di Sabatino, A Autoimmun Rev 2019-03-04 5.08 | Mar 8
Induction and Maintenance Treatment of Inflammatory Bowel Disease: A Comprehensive Review Jeong, D; Kim, S; Shin, J; et al Autoimmun Rev 2019-03-04 5.08 | Mar 8
Cellular and Molecular Therapeutic Targets in Inflammatory Bowel Disease-Focusing on Intestinal Barrier Function Schoultz, I; Keita, A Cells 2019-02-22 5.07 | Mar 1
Redefining the IBDs Using Genome-Scale Molecular Phenotyping Furey, T; Sethupathy, P; Sheikh, S Nat Rev Gastroenterol Hepatol 2019-02-20 5.06 | Feb 22
Cancer-Associated Fibroblasts in Gastrointestinal Cancer Kobayashi, H; Enomoto, A; Woods, S; Burt, A; Takahashi, M; Worthley, D Nat Rev Gastroenterol Hepatol 2019-02-18 5.06 | Feb 22
Function and Mechanisms of Enteroendocrine Cells and Gut Hormones in Metabolism Gribble, F; Reimann, F Nat Rev Endocrinol 2019-02-13 5.05 | Feb 15
Defective Proteostasis in Celiac Disease as a New Therapeutic Target Maiuri, L; Villella, V; Piacentini, M; Raia, V; Kroemer, G Cell Death Dis 2019-02-08 5.04 | Feb 8
Escherichia coli Pathobionts Associated with Inflammatory Bowel Disease Mirsepasi-Lauridsen, H; Vallance, B; Krogfelt, K; Petersen, A Clin Microbiol Rev 2019-01-30 5.03 | Feb 1
Crossing the Intestinal Barrier via Listeria Adhesion Protein and Internalin A Drolia, R; Bhunia, AK Trends Microbiol 2019-01-17 5.02 | Jan 25
Shortcuts to Intestinal Carcinogenesis by Genetic Engineering in Organoids Maru, Y; Onuma, K; Ochiai, M; Imai, T; Hippo, Y Cancer Sci 2019-01-13 5.01 | Jan 18
Cellular Plasticity in Intestinal Homeostasis and Disease de Sousa e Melo, F; de Sauvage, F Cell Stem Cell 2019-01-03 5.00 | Jan 11
Primary Cell-Derived Intestinal Models: Recapitulating Physiology Dutton, J; Hinman, S; Kim, R; Wang, Y; Allbritton, N Trends Biotechnol 2018-12-24 5.00 | Jan 11
Intestinal Organoids: A New Paradigm for Engineering Intestinal Epithelium In Vitro Rahmani, S; Breyner, N; Su, H; Verdu, E; Didar, T Biomaterials 2018-12-10 4.49 | Dec 21
Exosomes as a Novel Cell‐Free Therapeutic Approach in Gastrointestinal Diseases Baghaei, K; Tokhanbigli, S; Asadzadeh, H; Nmaki, S; Reza Zali, M; Hashemi, SM J Cell Physiol 2018-12-07 4.48 | Dec 14
Role of Epithelial-to-Mesenchymal Transition in Inflammatory Bowel Disease Lovisa, S; Genovese, G; Danese, S J Crohns Colitis 2018-12-06 4.47 | Dec 7
Modeling Human Digestive Diseases with CRISPR-Cas9-Modified Organoids Fujii, M; Clevers, H; Sato, T Gastroenterology 2018-11-23 4.46 | Nov 30
2D- and 3D-Based Intestinal Stem Cell Cultures for Personalized Medicine Liu, Y; Chen, YG Cells 2018-11-22 4.46 | Nov 30
Cannabis, Cannabinoids and the Endocannabinoid System – Is There Therapeutic Potential for Inflammatory Bowel Disease? Ambrose, T; Simmons, A J Crohns Colitis 2018-11-12 4.45 | Nov 23
Tales from the Crypt: New Insights into Intestinal Stem Cells Gehart, H; Clevers, H Nat Rev Gastroenterol Hepatol 2018-11-14 4.44 | Nov 16
Intestinal Fibrosis Lenti, MV; Di Sabatino, A Mol Aspects Med 2018-11-01 4.43 | Nov 9
Emerging Therapies for Inflammatory Bowel Disease Weisshof, R; El Jurdi, K; Zmeter, N; Rubin, DT Adv Ther 2018-10-29 4.42 | Nov 2
Cancer Pharmacoprevention: Targeting Polyamine Metabolism to Manage Risk Factors for Colon Cancer Gerner, EW; Bruckheimer, E; Cohen, A J Biol Chem 2018-10-24 4.41 | Oct 26
Diagnostic, Prognostic, and Therapeutic Potency of MicroRNA 21 in the Pathogenesis of Colon Cancer, Current Status and Prospective Bahreyni, A; Rezaei, M; Hassanian, S; et al J Cell Physiol 2018-10-14 4.40 | Oct 19
Mesenchymal Stromal Cell Therapy in Intestinal Diseases Ciccocioppo, R; Fioravante, M; Frulloni, L Curr Opin Organ Transplant 2018-10-08 4.39 | Oct 12
The Colorectal Cancer Epidemic: Challenges and Opportunities for Primary, Secondary and Tertiary Prevention Brenner, H; Chen, C Br J Cancer 2018-10-04 4.38 | Oct 5
Recent Progress in Organoid Culture to Model Intestinal Epithelial Barrier Functions Nakamura, T Int Immunol 2018-10-03 4.38 | Oct 5
Studying Cellular Heterogeneity and Drug Sensitivity in Colorectal Cancer Using Organoid Technology Sasaki, N; Clevers, H Curr Opin Genet Dev 2018-09-24 4.37 | Sep 28
Cellular Interactions in the Intestinal Stem Cell Niche Pastula, A; Marcinkiewicz, J Arch Immunol Ther Exp (Warsz) 2018-09-21 4.37 | Sep 28
Progress and Potential in Organoid Research Rossi, G; Manfrin, A; Lutolf, MP Nat Rev Genet 2018-09-18 4.36 | Sep 21
Tales from the Crypt: Intestinal Niche Signals in Tissue Renewal, Plasticity and Cancer Spit, M; Koo, BK; Maurice, MM Open Biol 2018-09-12 4.35 | Sep 14
The Intestinal Stem Cell Niche: Homeostasis and Adaptations Santos, A; Lo, Y; Mah, A; Kuo, C Trends Cell Biol 2018-09-05 4.34 | Sep 7
Targeting the Paracrine Hormone-Dependent Guanylate Cyclase/cGMP/Phosphodiesterases Signaling Pathway for Colorectal Cancer Prevention Yarla, N; Gali, H; Rao, C; et al Semin Cancer Biol 2018-09-03 4.34 | Sep 7
Energy Balance and Gastrointestinal Cancer: Risk, Interventions, Outcomes and Mechanisms Ulrich, C; Himbert, C; Holowatyj, A; Hursting, S Nat Rev Gastroenterol Hepatol 2018-08-29 4.33 | Aug 31
Potential Use of Human Stem Cell-Derived Intestinal Organoids to Study Inflammatory Bowel Diseases Dotti, I; Salas, A AAPS J 2018-08-29 4.33 | Aug 31
Reserve Stem Cells in Intestinal Homeostasis and Injury Bankaitis, ED; Ha, A; Kuo, CJ; Magness, ST Gastroenterology 2018-08-14 4.32 | Aug 24
Organoids for Drug Discovery and Personalized Medicine Takahashi, T; None Annu Rev Pharmacol Toxicol 2018-08-16 4.31 | Aug 16
Rebuilding the Gut Microbiota Ecosystem Gagliardi, A; Totino, V; Shippa, S; et al Int J Environ Res Public Health 2018-08-07 4.30 | Aug 10
Neuroimmunophysiology of the Gut: Advances and Emerging Concepts Focusing on the Epithelium Sharkey, K; Beck, P; McKay, D Nat Rev Gastroenterol Hepatol 2018-08-01 4.29 | Aug 3
Targeting JAK-STAT Signal Transduction in IBD Soendergaard, C; Bergenheim, F; Bjerrum, J; Nielsen, O Pharmacol Ther 2018-07-23 4.28 | Jul 27
Brief Summary of the Current Protocols for Generating Intestinal Organoids Miura, S; Suzuki, A Dev Growth Differ 2018-07-23 4.28 | Jul 27
Advances in Understanding the Role of Cytokines in Inflammatory Bowel Disease Bevivino, G; Monteleone, G Expert Rev Gastroenterol Hepatol 2018-07-19 4.27 | Jul 20
Janus Kinase Inhibitors for the Treatment of Inflammatory Bowel Diseases: Developments from Phase I and Phase II Clinical Trials D’Amico, F; Fiorino, G; Furfaro, F; Alloca, M; Danese, S Expert Opin Investig Drugs 2018-07-06 4.26 | Jul 13
Patient-Derived Tumor Organoids for Prediction of Cancer Treatment Response Nagle, PW; Plukker, JTM; Muijs, CT; van Luijk, P; Coppes, RP Semin Cancer Biol 2018-06-30 4.25 | Jul 5
iPSC-Derived Enterocyte-Like Cells for Drug Absorption and Metabolism Studies Macedo, MH; Araújo, F; Martinez, E; Barrias, C; Sarmento, B Trends Mol Med 2018-06-23 4.24 | Jun 29
Inflammatory Bowel Disease: New Therapies from Antisense Oligonucleotides Marafini, I; Monteleone, G Ann Med 2018-06-16 4.23 | Jun 22
The Current State of the Art for Biological Therapies and New Small Molecules in Inflammatory Bowel Disease Paramsothy, S; Rosenstein, AK; Mehandru, S; Colombel, JF Mucosal Immunol 2018-06-15 4.22 | Jun 15
Application of Porcine Gastrointestinal Organoid Units as a Potential In Vitro Tool for Drug Discovery and Development Olayanju, A; Jones, L; Greco, K; Goldring, CE; Ansari, T J Appl Toxicol 2018-06-11 4.22 | Jun 15
Development of an Experimental Model for Analyzing Drug Resistance in Colorectal Cancer Elbadawy, M; Usui, T; Yamawaki, H; Sasaki, K Cancers 2018-05-28 4.21 | Jun 8
Mitochondrial Function — Gatekeeper of Intestinal Epithelial Cell Homeostasis Rath, E; Moschetta, A; Haller, D Nat Rev Gastroenterol Hepatol 2018-05-29 4.20 | Jun 1
Targeting LGR5 in Colorectal Cancer: Therapeutic Gold or Too Plastic? Morgan, RG; Mortensson, E; Williams, AC Br J Cancer 2018-05-30 4.20 | Jun 1
Intestinal Organoids for Modeling Intestinal Development and Disease Fair, KL; Colquhoun, J; Hannan, NRF Philos Trans R Soc Lond B Biol Sci 2018-05-21 4.19 | May 25
Current Status of 3D Organoids as Pre‐Clinical Models Kaushik, G; Ponnusamy, MP; Batra, SK Stem Cells 2018-05-17 4.18 | May 17
NADPH Oxidases and ROS Signaling in the Gastrointestinal Tract Aviello, G; Knaus, UG Mucosal Immunol 2018-05-09 4.17 | May 11
The Intestinal Epithelium: Central Coordinator of Mucosal Immunity Allaire, JM; Crowley, SM; Law, HT; Chang, S; Ko, H; Vallance, B Trends Immunol 2018-04-28 4.16 | May 4
Long Non-Coding RNAs: Crucial Regulators of Gastrointestinal Cancer Cell Proliferation Chen, J; Liu, S; Hu, X Cell Death Discov 2018-04-27 4.15 | Apr 27
Th9 Cells: Probable Players in Ulcerative Colitis Pathogenesis Shohan, M; Elahi, S; Shirzad, H; Rafieian-Kopaei, M; Bagheri, N; Soltani, E Int Rev Immunol 2018-04-19 4.14 | Apr 20
Lessons from the Crypt: HMGA1—Amping Up Wnt for Stem Cells and Tumor Progression Resar, L; Chia, L; Xian, L Cancer Res 2018-04-04 4.13 | Apr 13
RNA Binding Proteins in Intestinal Epithelial Biology and Colorectal Cancer Chatterji, P; Rustgi, AK Trends Mol Med 2018-04-04 4.12 | Apr 6
Integration of Sensors in Gastrointestinal Organoid Culture for Biological Analysis Kim, G; Ginga, NJ; Takayama, S Cell Mol Gastroenterol Hepatol 2018-03-26 4.12 | Apr 6
Mechanisms for Intestinal Regeneration Dubrovsky, G; Dunn, JCY Curr Opin Pediatr 2018-03-13 4.11 | Mar 23
Immunopathogenesis of Inflammatory Bowel Disease and Mechanisms of Biological Therapies Ahluwalia, B; Moraes, L; Magnusson, MK; Ohman, L Scand J Gastroenterol 2018-03-09 4.10 | Mar 16
Wnt Signaling in Intestinal Stem Cells: Lessons from Mice and Flies Perochon, J; Carroll, LR; Cordero, JB Genes (Basel) 2018-03-02 4.09 | Mar 9
Organs-on-a-Chip: A Fast Track for Engineered Human Tissues in Drug Development Ronaldson-Bouchard, K; Vunjak-Novakovic, G Cell Stem Cell 2018-03-01 4.08 | Mar 2
The Intestinal Complement System in Inflammatory Bowel Disease: Shaping Intestinal Barrier Function Sina, C; Kemper, C; Derer, S Semin Immunol 2018-02-24 4.08 | Mar 2
Recent Advances in Lgr5+ Stem Cell Research Leung, C; Tan, SH; Barker, N Trends Cell Biol 2018-02-21 4.07 | Feb 23
Extracellular Vesicles Regulate Immune Responses and Cellular Function in Intestinal Inflammation and Repair Bui, TM; Mascarenhas, LA; Sumagin, R Tissue Barriers 2018-02-09 4.06 | Feb 16
Essential Immunologic Orchestrators of Intestinal Homeostasis Zhou, L; Sonnenberg, GF Sci Immunol 2018-02-09 4.05 | Feb 9
Circulating Tumor Cell-Derived Organoids: Current Challenges and Promises in Medical Research and Precision Medicine Praharaj, PP; Bhutia, SK; Nagrath, S; Bitting, RL; Deep, G Biochim Biophys Acta 2018-01-31 4.04 | Feb 2
Personalized Cancer Medicine: An Organoid Approach Aboulkheyr Es, H; Montazeri, L; Aref, AR; Vosough, M; Baharvand, H Trends Biotechnol 2018-01-20 4.03 | Jan 26
Role of the IL-33/ST2L Axis in Colorectal Cancer Progression Akimoto, M; Tekenaga, K Cell Immunol 2018-01-09 4.02 | Jan 19
Wnt, RSPO and Hippo Signaling in the Intestine and Intestinal Stem Cells Kriz, V; Korinek, V Genes (Basel) 2018-01-08 4.01 | Jan 12
Regenerating Human Epithelia with Cultured Stem Cells: Feeder Cells, Organoids and Beyond Hynds, RE; Bonfanti, P; Janes, SM EMBO Mol Med 2017-12-29 4.00 | Jan 5
Intestinal Stem Cells to Advance Drug Development, Precision, and Regenerative Medicine: A Paradigm Shift in Translational Research Mochel, JP; Jergens, AE; Kingsbury, D; Kim, HJ; Martín, MG; Allenspach, K AAPS J 2017-12-12 3.48 | Dec 15
Biomaterials-Based Approaches to Tumor Spheroid and Organoid Modeling Thakuri, PS; Liu, C; Luker, GD; Tavana, H Adv Healthc Mater 2017-12-04 3.47 | Dec 8
Cellular Senescence in Gastrointestinal Diseases: From Pathogenesis to Therapeutics Frey, N; Venturelli, S; Zender, L; Bitzer, M Nat Rev Gastroenterol Hepatol 2017-11-29 3.46 | Dec 1
Pathology and Genetics of Hereditary Colorectal Cancer Ma, H; Brosens, LAA; Offerhaus, GJA; Giardiello, FM; de Leng, WWJ; Montgomery, EA Pathology 2017-12-01 3.46 | Dec 1
Bacteriophages Targeting Intestinal Epithelial Cells: A Potential Novel Form of Immunotherapy Górski, A; Jończyk-Matysiak, E; Łusiak-Szelachowska, M; Międzybrodzki, R; Weber-Dąbrowska, B; Borysowski, J Cell Mol Life Sci 2017-11-21 3.45 | Nov 24
The Clinical and Biological Roles of Transforming Growth Factor Beta in Colon Cancer Stem Cells: A Systematic Review Chruścik, A; Gopalan, V; Lam, AK Eur J Cell Biol 2017-11-08 3.44 | Nov 17
Emerging Tumor Spheroids Technologies for 3D In Vitro Cancer Modeling Rodrigues, T; Kundu, B; Silva-Correia, J; Kundu, SC; Oliveira, JM; Reis, RL; Correlo, VM Pharmacol Ther 2017-10-30 3.43 | Nov 10
The Impact of Dietary Polyphenols on COX-2 Expression in Colorectal Cancer Owczarek, K; Lewandowska, U Nutr Cancer 2017-10-25 3.42 | Nov 3
Next Generation Organoids for Biomedical Research and Applications Lou, YR; Leung, AW Biotechnol Adv 2017-10-19 3.41 | Oct 27
Endocannabinoid-Related Compounds in Gastrointestinal Diseases Pesce, M; D’Alessandro, A; Borrelli, O; Gigli, S; Seguella, L; Cuomo, R; Esposito, G; Sarnelli, G J Cell Mol Med 2017-10-09 3.40 | Oct 20
The Role of Intestinal Stem Cells in Epithelial Regeneration Following Radiation-Induced Gut Injury Kim, C-Y; Yang, VW; Bialkowska, AB Curr Stem Cell Rep 2017-10-05 3.39 | Oct 13
Safety and Efficacy of Nintedanib for the Treatment of Metastatic Colorectal Cancer Riesco-Martinez, MC; Sanchez Torre, A; García-Carbonero, R Expert Opin Investig Drugs 2017-10-02 3.38 | Oct 6
Cell Plasticity in Epithelial Homeostasis and Tumorigenesis Varga, J; Greten, FR Nat Cell Biol 2017-09-25 3.37 | Sep 29
3D Intestinal Organoids in Metabolic Research: Virtual Reality in a Dish Tsakmaki, A; Pedro, PF; Bewick, GA Curr Opin Pharmacol 2017-09-29 3.37 | Sep 29
The Potential for Gut Organoid Derived Interstitial Cells of Cajal in Replacement Therapy Zhou, J; O’Connor, MD; Ho, V Int J Mol Sci 2017-09-26 3.37 | Sep 29
Deciphering Cell Intrinsic Properties: A Key Issue for Robust Organoid Production Picollet-D’hahan, N; Dolega, ME; Freida, D; Martin, DK; Gidrol, X Trends Biotechnol 2017-09-16 3.36 | Sep 22
Functional Significance and Therapeutic Implication of Ring-Type E3 Ligases in Colorectal Cancer Liu, L; Wong, CC; Gong, B; Yu, J Oncogene 2017-09-18 3.36 | Sep 22
Novel Insights into Microbiome in Colitis and Colorectal Cancer Yang, Y; Jobin, C Curr Opin Gastroenterol 2017-09-05 3.35 | Sep 15
Role of SMAD Proteins in Colitis-Associated Cancer: From Known to the Unknown Chandrasinghe, P; Cereser, B; Moorghen, M; Al Bakir, I; Tabassum, N; Hart, A; Stebbing, J; Warusavitarne, J Oncogene 2017-09-04 3.34 | Sep 8
Intestinal Hypoxia and Hypoxia-Induced Signaling as Therapeutic Targets for IBD Van Welden, S; Selfridge, AC; Hindryckx, P Nat Rev Gastroenterol Hepatol 2017-08-30 3.33 | Sep 1
Enteroendocrine Cells-Sensory Sentinels of the Intestinal Environment and Orchestrators of Mucosal Immunity Worthington, JJ; Reimann, F; Gribble, FM Mucosal Immunol 2017-08-30 3.33 | Sep 1
Therapeutic Potential of Amino Acids in Inflammatory Bowel Disease Liu, Y; Wang, X; Hu, CA Nutrients 2017-08-23 3.32 | Aug 25
Extrinsic Control of Wnt Signaling in the Intestine Koch, S Differentiation 2017-08-05 3.31 | Aug 18
Perianal Fistulizing Crohn’s Disease: Pathogenesis, Diagnosis and Therapy Panés, J; Rimola, J Nat Rev Gastroenterol Hepatol 2017-08-09 3.30 | Aug 11
Anti-EGFR Monoclonal Antibody Panitumumab for the Treatment of Patients with Metastatic Colorectal Cancer: An Overview of Current Practice and Future Perspectives Battaglin, F; Dadduzio, V; Bergamo, F; Manai, C; Schirripa, M; Lonardi, S; Zagonel, V; Loupakis, F Expert Opin Biol Ther 2017-07-28 3.29 | Aug 4
Role of ADAM10 in Intestinal Crypt Homeostasis and Tumorigenesis Dempsey, PJ Biochim Biophys Acta 2017-07-22 3.28 | Jul 28
Tumor Organoids as a Pre-Clinical Cancer Model for Drug Discovery Weeber, F; Ooft, SN; Dijkstra, KN; Voest, EE Cell Chem Biol 2017-07-27 3.28 | Jul 28
Proteomics in Inflammatory Bowel Disease: Approach Using Animal Models Mourad, FH; Yau, Y; Wasinger, VC; Leong, RW Dig Dis Sci 2017-07-17 3.27 | Jul 21
The Extracellular Matrix of the Gastrointestinal Tract: A Regenerative Medicine Platform Hussey, GS; Keane, TJ; Badylak, SF Nat Rev Gastroenterol Hepatol 2017-07-12 3.26 | Jul 14
Dclk1-Expressing Tuft Cells: Critical Modulators of the Intestinal Niche? Middelhoff, M; Westphalen, CB; Hayakawa, Y; Yan, KS; Gershon, MD; Wang, TC; Quante, M Am J Physiol Gastrointest Liver Physiol 2017-07-06 3.26 | Jul 14
Multifaceted Interpretation of Colon Cancer Stem Cells Hatano, Y; Fukuda, S; Hisamatsu, K; Hirata, A; Hara, A; Tomita, H Int J Mol Sci 2017-07-05 3.25 | Jul 7
Intestinal Lymphatic Vasculature: Structure, Mechanisms and Functions Bernier-Latmani, J; Petrova, TV Nat Rev Gastroenterol Hepatol 2017-06-28 3.24 | Jun 30
Bioengineering for Intestinal Organoid Cultures Kim, GA; Spence, JR; Takayama, S Curr Opin Biotechnol 2017-06-21 3.24 | Jun 30
Signaling and Epigenetic Mechanisms of Intestinal Stem Cells and Progenitors: Insight into Crypt Homeostasis, Plasticity, and Niches Smith, RJ; Rao-Bhatia, A; Kim, TH Wiley Interdiscip Rev Dev Biol 2017-06-23 3.24 | Jun 30
Intestinal Barrier Integrity and Inflammatory Bowel Disease: Stem Cell-Based Approaches to Regenerate the Barrier Holmberg, FEO; Pedersen, J; Jørgensen, P; Soendergaard, C; Jensen, KB; Nielsen, OH J Tissue Eng Regen Med 2017-06-21 3.23 | Jun 23
Systematic Review with Meta-Analysis: The Efficacy and Safety of Stem Cell Therapy for Crohn’s Disease Qiu, Y; Li, MY; Feng, T; Feng, R; Mao, R; Chen, BL; He, Y; Zeng, ZR; Zhang, SH; Chen, MH Stem Cell Res Ther 2017-06-06 3.22 | Jun 16
Genetic and Epigenetic Markers in Colorectal Cancer Screening: Recent Advances Singh, MP; Rai, S; Suyal, S; Singh, SK; Singh, NK; Agarwal, A; Srivastava, S Expert Rev Mol Diagn 2017-05-31 3.21 | Jun 9
Strategies for Targeted Drug Delivery in Treatment of Colon Cancer: Current Trends and Future Perspectives Banerjee, A; Pathak, S; Devi, SV; Vasan, D; Murugesan, R; Verma, RS Drug Discov Today 2017-05-22 3.20 | Jun 2
Role of TGF-β in Metastatic Colon Cancer: It Is Finally Time for Targeted Therapy Villalba, M; Evans, SR; Vidal-Vanaclocha, F; Calvo, A Cell Tissue Res 2017-05-30 3.20 | Jun 2
Roles of Intestinal Epithelial Cells in the Maintenance of Gut Homeostasis Okumura, R; Takeda, K Exp Mol Med 2017-05-26 3.19 | May 26
Molecular Basis of Alcohol-Related Gastric and Colon Cancer Na, HK; Lee, JY Int J Mol Sci 2017-05-24 3.19 | May 26
Intestinal Epithelial Claudins: Expression and Regulation in Homeostasis and Inflammation Garcia-Hernandez, V; Quiros, M; Nusrat, A Ann N Y Acad Sci 2017-05-10 3.18 | May 19
Non-Conventional Features of Peripheral Serotonin Signaling — The Gut and Beyond Spohn, SN; Mawe, GM Nat Rev Gastroenterol Hepatol 2017-05-10 3.17 | May 12
NSAIDActivated Gene 1 and Its Implications for Mucosal Integrity and Intervention beyond NSAIDs Moon, Y Pharmacol Res 2017-04-25 3.16 | May 5
Bile Acids and Colon Cancer: Is FXR the Solution of the Conundrum? Gadaleta, RM; Garcia-Irigoyen, O; Moschetta, A Mol Aspects Med 2017-04-21 3.15 | Apr 28
Molecular Subtypes in Cancers of the Gastrointestinal Tract Bijlsma, MF; Sadanandam, A; Tan, P; Vermeulen, L Nat Rev Gastroenterol Hepatol 2017-04-12 3.14 | Apr 21
Targeting C-MET in Gastrointestinal Tumors: Rationale, Opportunities and Challenges Bradley, CA; Salto-Tellez, M; Laurent-Puig, P; Bardelli, A; Rolfo, C; Tabernero, J; Khawaja, HA; Lawler, M; Johnston, PG; Schaeybroeck, SV; MErCuRIC, consortium Nat Rev Clin Oncol 2017-04-04 3.13 | Apr 7
Therapeutic Drug Monitoring of Golimumab in the Treatment of Ulcerative Colitis Vande Casteele, N; Khanna, R Pharm Res 2017-04-03 3.13 | Apr 7
Disease Modeling in Stem Cell-Derived 3D Organoid Systems Dutta, D; Heo, I; Clevers, H Trends Mol Med 2017-03-21 3.12 | Mar 31
Contributions of Intestinal Epithelial Barriers to Health and Disease Choi, W; Yeruva, S; Turner, JR Exp Cell Res 2017-03-23 3.12 | Mar 31
A Unified Model of the Hierarchical and Stochastic Theories of Gastric Cancer Song, Y; Wang, Y; Tong, C; Xi, H; Zhao, X; Wang, Y; Chen, L Br J Cancer 2017-03-16 3.11 | Mar 24
Autologous Hematopoietic Stem Cells for Refractory Crohn’s Disease DiNicola, CA; Zand, A; Hommes, DW Expert Opin Biol Ther 2017-03-22 3.11 | Mar 24
Microbiota: A Key Orchestrator of Cancer Therapy Roy, S; Trinchieri, G Nat Rev Cancer 2017-03-17 3.10 | Mar 17
Stem Cell Therapy for Inflammatory Bowel Disease Lightner, AL Clin Transl Gastroenterol 2017-03-16 3.10 | Mar 17
Gut Microbiota Modulation of Chemotherapy Efficacy and Toxicity Alexander, JL; Wilson, ID; Teare, J; Marchesi, JR; Nicholson, JK; Kinross, JM Nat Rev Gastroenterol Hepatol 2017-03-08 3.09 | Mar 10
Stem Cell Therapy for Inflammatory Bowel Disease Lightner, AL Clin Transl Gastroenterol 2017-03-09 3.09 | Mar 10
Systematic Review with Meta-Analysis: The Efficacy and Safety of CT-P13, a Biosimilar of Anti-Tumor Necrosis Factor-α Agent (Infliximab), in Inflammatory Bowel Diseases Komaki, Y; Yamada, A; Komaki, F; Micic, D; Ido, A; Sakuraba, A Aliment Pharmacol Ther 2017-02-26 3.08 | Mar 3
Nucleic Acid Sensing Pattern Recognition Receptors in the Development of Colorectal Cancer and Colitis He, L; Chen, Y; Wu, Y; Xu, Y; Zhang, Z; Liu, Z Cell Mol Life Sci 2017-02-21 3.07 | Feb 24
Carcinogenesis and Therapeutics: The Microbiota Perspective Tsilimigras, MCB; Fodor, A; Jobin, C Nat Microbiol 2017-02-22 3.07 | Feb 24
Lipocalin-2: A Master Mediator of Intestinal and Metabolic Inflammation Moschen, AR; Adolph, TE; Gerner, RR; Wieser, V; Tilg, H Trends Endocrinol Metab 2017-02-14 3.06 | Feb 17
Organoid Technologies Meet Genome Engineering Nie, J; Hashino, E EMBO Rep 2017-02-15 3.06 | Feb 17
Clonal Evolution of Colorectal Cancer in IBD Choi, C-H R; Bakir, IA; Hart, AL; Graham, TA Nat Rev Gastroenterol Hepatol 2017-02-08 3.05 | Feb 10
Current and Emerging Therapeutic Targets for IBD Neurath, MN Nat Rev Gastroenterol Hepatol 2017-02-01 3.04 | Feb 3
Evolutionary and Ecological Forces That Shape the Bacterial Communities of the Human Gut Messer, JS; Liechty, ER; Vogel, OA; Chang, EB Mucosal Immunol 2017-02-01 3.04 | Feb 3
Stem Cell Treatment in Crohn’s Disease Zhang, XM; Zhang, YJ; Wang, W; Wei, YQ; Deng, H Hum Gene Ther 2017-01-28 3.04 | Feb 3
Genome Engineering of Stem Cell Organoids for Disease Modeling Sun, Y; Ding, Q Protein Cell 2017-01-19 3.03 | Jan 27
The Heterocellular Emergence of Colorectal Cancer Tape, CJ Trends Cancer 2017-01-20 3.03 | Jan 27
Neuroimmune Regulation During Intestinal Development and Homeostasis Veiga-Fernandes, H; Pachnis, V Nat Immunol 2017-01-16 3.02 | Jan 20
The Mucosal Immune System: Master Regulator of Bidirectional Gut–Brain Communications Powell, N; Walker, MN; Talley, NJ Nat Rev Gastroenterol Hepatol 2017-01-18 3.02 | Jan 20
Crosstalk between Intestinal Epithelial Cell and Adaptive Immune Cell in Intestinal Mucosal Immunity Lu, JT; Xu, AT; Shen, J; Ran, ZH J Gastroenterol Hepatol 2017-01-10 3.01 | Jan 13
Collateral Damage: Insights into Bacterial Mechanisms That Predispose Host Cells to Cancer Gagnaire, A; Nadel, B; Raoult, D; Neefjes, J; Gorvel, J-P Nat Rev Microbiol 2017-01-03 3.00 | Jan 6
Meta-Analytic Bayesian Model For Differentiating Intestinal Tuberculosis from Crohn’s Disease Limsrivilai, J; Shreiner, AB; Pongpaibul, A; Laohapand, C; Boonanuwat, R; Pausawasdi, N; Pongprasobchai, S; Manatsathit, S; Higgins, PDR Am J Gastroenterol 2017-01-03 3.00 | Jan 6
Eicosanoid Receptors: Targets for the Treatment of Disrupted Intestinal Epithelial Homeostasis Moreno, JJ Eur J Pharmacol 2016-12-06 2.46 | Dec 16
Ulcerative Colitis Ungaro, R; Mehandru, S; Allen, PB; Peyrin-Biroulet, L; Colombel, JF Lancet 2016-11-30 2.45 | Dec 9
From Tumor Heterogeneity to Advances in Precision Treatment of Colorectal Cancer Punt, CJA; Koopman, M; Vermeulen, L Nat Rev Clin Oncol 2016-12-06 2.45 | Dec 9
Novel Therapies in Inflammatory Bowel Disease: An Evaluation of the Evidence Narula, N; Rubin, DT; Sands, BE Am J Gastroenterol 2016-12-01 2.44 | Dec 2
Therapeutic Targets in Inflammatory Bowel Disease: Current and Future Bilsborough, J; Targan, SR; Snapper, SB Am J Gastroenterol 2016-12-01 2.44 | Dec 2
Intestinal Stem Cell Transplantation Nakamura, T; Watanabe, M J Gastroenterol 2016-11-25 2.44 | Dec 2
Mesenchymal Stromal Cell Therapy for Inflammatory Bowel Diseases Grégoire, C; Lechanteur, C; Briquet, A; Baudoux, É; Baron, F; Louis, E; Beguin, Y Aliment Pharmacol Ther 2016-11-22 2.43 | Nov 25
The Intestinal Epithelial Barrier: A Therapeutic Target? Matthew A. Odenwald & Jerrold R. Turner Nat Rev Gastroenterol Hepatol 2016-11-16 2.42 | Nov 18
Role of Endoscopy in Early Esophageal Cancer Mannath, J; Ragunath, K Nat Rev Gastroenterol Hepatol 2016-11-03 2.41 | Nov 4
The Genetic Background of Inflammatory Bowel Disease: From Correlation to Causality Uniken Venema, WT; Voskuil, MD; Dijkstra, G; Weersma, RK; Festen, EA J Pathol 2016-10-26 2.40 | Oct 28
Epithelial Glycosylation in Gut Homeostasis and Inflammation Goto, Y; Uematsu, S; Kiyono, H Nat Immunol 2016-10-19 2.39 | Oct 21
Human Intestinal Barrier Function in Health and Disease König, J; Wells, J; Cani, PD; García-Ródenas, CL; MacDonald, T; Mercenier, A; Whyte, J; Troost, F; Brummer, RJ Clin Transl Gastroenterol 2016-10-20 2.39 | Oct 21
Paneth Cell Alterations in the Development and Phenotype of Crohn’s Disease Stappenbeck, TS; McGovern, DP Gastroenterology 2016-10-08 2.38 | Oct 14
Tuft Cells: New Players in Colitis Steele, SP; Melchor, SJ; Petri, WA Trends Mol Med 2016-10-04 2.37 | Oct 7
Human Mini-Guts: New Insights into Intestinal Physiology and Host-Pathogen Interactions In, JG; Foulke-Abel, J; Estes, MK; Zachos, NC; Kovbasnjuk, O; Donowitz, M Nat Rev Gastroenterol Hepatol 2016-09-28 2.36 | Sep 30
Organoids: Modeling Development and the Stem Cell Niche in a Dish Kretzschmar, K; Clevers, H Dev Cell 2016-09-26 2.36 | Sep 30
Molecular Pathways Driving Disease-Specific Alterations of Intestinal Epithelial Cells López-Posadas, R; Neurath, MF; Atreya, I Cell Mol Life Sci 2016-09-13 2.35 | Sep 23
Concise Review: The Potential Use of Intestinal Stem Cells to Treat Patients With Intestinal Failure Hong, SN; Dunn, JC; Stelzner, M; Martín, MG Stem Cells Transl Med 2016-09-16 2.35 | Sep 23
Modeling Infectious Diseases and Host-Microbe Interactions in Gastrointestinal Organoids Bartfield, S Dev Biol 2016-09-14 2.35 | Sep 23
Intestinal Organoids: New Frontiers in the Study of Intestinal Disease and Physiology. Wallach, Thomas E; Bayrer, James R J Pediatr Gastroenterol Nutr 2016-09-14 2.34 | Sep 16
Intestinal Organoids as a Novel Tool to Study Microbes-Epithelium Interactions Nigro, G; Hanson, M; Fevre, C; Lecuit, M; Sansonetti, P.J Methods Mol Biol 2016-09-15 2.34 | Sep 16
Neuroendocrine Peptide Mechanisms Controlling Intestinal Epithelial Function Cox, HM Curr Opin Pharmacol 2016-09-03 2.33 | Sep 9
Acute Severe Ulcerative Colitis: From Pathophysiology to Clinical Management Hindryckx, P; Jairath, V; D’Haens, G Nat Rev Gastroenterol Hepatol 2016-09-01 2.32 | Sep 2
Thyroid Hormone Regulation of Adult Intestinal Stem Cells: Implications on Intestinal Development and Homeostasis Sun, G; Roediger, J; Shi, YB Rev Endocr Metab Disord 2016-08-23 2.31 | Aug 26
Gastrointestinal Organoids: How They Gut It Out Merker, SR; Weitz, J; Strange, DE Dev Biol 2016-08-10 2.30 | Aug 19
Bioengineering the Gut: Future Prospects of Regenerative Medicine Bitar, KN; Zakhem, E Nat Rev Gastroenterol Hepatol 2016-08-10 2.29 | Aug 12
The Culture of Gut Explants: A Model to Study the Mucosal Response Russo, I; Zeppa, P; Iovino, P; Del Giorno, C; Zingone, F; Bucci, C; Puzziello, A; Ciacci, C J Immunol Methods 2016-07-28 2.28 | Aug 5
Developments in Methods for Measuring the Intestinal Absorption of Nanoparticle-Bound Drugs Liu, W; Pan, H; Zhao, L; Zhao, R; Zhu, Y; Pan, W Int J Mol Sci 2016-07-21 2.27 | Jul 29
Inflammation and the Intestinal Barrier: Leukocyte-Epithelial Cell Interactions, Cell Junction Remodeling, and Mucosal Repair Luissint, AC; Parkos, CA; Nusrat, A Gastroenterology 2016-07-16 2.26 | Jul 22
The Role of Stem Cell DNA Methylation in Colorectal Carcinogenesis Song, L; Li, Y Stem Cell Rev 2016-07-11 2.24 | Jul 15
Sporadic Colorectal Cancer: Microbial Contributors to Disease Prevention, Development and Therapy Drewes, JL; Housseau, F; Sears, CL Br J Cancer 2016-07-05 2.24 | Jul 8
Mouse Models of Intestinal Inflammation and Cancer Westbrook, AM; Szakmary, A; Schiestl, RH Arch Toxicol 2016-06-16 2.23 | Jun 24
hPSC-Derived Lung and Intestinal Organoids as Models of Human Fetal Tissue Aurora, M; Spence, JR Dev Biol 2016-06-07 2.22 | Jun 17
Noncoding RNA and Colorectal Cancer: Its Epigenetic Role Kita, Y; Yonemori, K; Osako, Y; Baba, K; Mori, S; Maemura, K; Natsugoe, S J Hum Genet 2016-06-09 2.21 | Jun 10
The Cross-Talk between Enterocytes and Intraepithelial Lymphocytes Vitale, S; Picascia, S; Gianfrani, C Mol Cell Pediatr 2016-06-01 2.20 | Jun 3
Vagal Neurocircuitry and Its Influence on Gastric Motility Alberto Travagli, R; Anselmi, L Nat Rev Gastroenterol Hepatol 2016-05-25 2.19 | May 27
Advances in the Transepithelial Transport of Nanoparticles Yu, M; Yang, Y; Zhu, C; Guo, S; Gan, Y Drug Discov Today 2016-05-16 2.18 | May 20
The Hippo Pathway in Intestinal Regeneration and Disease Hong, AW; Meng, Z; Guan, KL Nat Rev Gastroenterol Hepatol 2016-05-05 2.17 | May 13
The Third Dimension: New Developments in Cell Culture Models for Colorectal Research Pereira, JF; Awatade, NT; Loureiro, CA; Matos, P; Amaral, MD; Jordan, P Cell Mol Life Sci 2016-05-04 2.17 | May 13
Intestinal Stem Cell Response to Injury: Lessons from Drosophila Jiang, H; Tian, A; Jiang, J Cell Mol Life Sci 2016-05-02 2.16 | May 6
Stem Cell Dynamics and Pretumor Progression in the Intestinal Tract Ma, H; Morsink, FH; Offerhaus, GJ; de Leng, WW J Gastroenterol 2016/04/23 2.15 | Apr 29
Gastrointestinal Stem Cells in Health and Disease: From Flies to Humans Li, H; Jasper, H Dis Model Mech 2016-04-25 2.15 | Apr 29
Mucosal Pathobiology and Molecular Signature of Epithelial Barrier Dysfunction in the Small Intestine in Irritable Bowel Syndrome González-Castro, AM; Martínez, C; Salvo-Romero, E; Fortea, M; Pardo-Camacho, C; Pérez-Berezo, T; Alonso-Cotoner, C; Santos, J; Vicario, M J Gastroenterol Hepatol 2016-04-18 2.14 | Apr 22
Current Evidence Supporting Mucosal Healing and Deep Remission as Important Treatment Goals for Inflammatory Bowel Disease Pineton de Chambrun, G; Blanc, P; Peyrin-Biroulet, L Expert Rev Gastroenterol Hepatol 2016-04-04 2.12 | Apr 8
MicroRNAs in Colorectal Carcinoma – from Pathogenesis to Therapy Chi, Y; Zhou, D J Exp Clin Cancer Res 2016-03-10 2.10 | Mar 18
Intestinal Stem Cells and Intestinal Homeostasis in Health and in Inflammation: A Review Bloemendaal, AL; Buchs, NC; George, BD; Guy, RJ Surgery 2016-02-27 2.09 | Mar 11
Organoids as an In Vitro Model of Human Development and Disease Fatehullah, A; Hui Tan, S; Barker, N Nat Cell Biol 2016-02-25 2.08 | Mar 4
Mechanism of Action of Anti-TNF Therapy in Inflammatory Bowel Disease Levin, AD; Wildenberg, ME; van den Brink, GR J Crohns Colitis 2016-02-19 2.07 | Feb 26
Exploring Interactions between Pathogens and the Drosophila Gut Mistry, R; Kounatidis, I; Ligoxygakis, P Dev Comp Immunol 2016-02-11 2.06 | Feb 19
Notch Regulation of Gastrointestinal Stem Cells Demitrack, ES; Samuelson, LC J Physiol 2016-02-05 2.05 | Feb 12
Plasticity of the Brush Border — the Yin and Yang of Intestinal Homeostasis Delacour, D; Salomon, J; Robine, S; Louvard, D Nat Rev Gastroenterol Hepatol 2016/02/03 2.04 | Feb 5
Blood-Based Biomarkers for Diagnosis, Prognosis and Treatment of Colorectal Cancer Yörüker, EE; Holdenrieder, S; Gezer, U Clin Chim Acta 2016-01-18 2.03 | Jan 29
Reparative Inflammation Takes Charge of Tissue Regeneration Karin, M; Clevers, H Nature 2016-01-20 2.02 | Jan 22
Organoid Models of Human Gastrointestinal Development and Disease Dedhia, PH; Bertaux-Skeirik, N; Zavros, Y; Spence, JR Gastroenterology 2016-01-13 2.02 | Jan 22
Engineering Stem Cell Organoids Yin, X; Mead, BE; Safaee, H; Langer, R; Karp, JM; Levy, O Cell Stem Cell 2016-01-07 2.01 | Jan 15
Human Enteroids/Colonoids and Intestinal Organoids Functionally Recapitulate Normal Intestinal Physiology and Pathophysiology Zachos, NC; Kovbasnjuk, O; Foulke-Abel, J; In, J; Blutt, SE; De Jonge, HR; Estes, MK; Donowitz, M J Biol Chem 2015-12-16 1.39 | Dec 18
Constructing Personalized Longitudinal Holo’omes of Colon Cancer-Prone Humans and Their Modeling in Flies and Mice Panagi, M; Georgila, K; Eliopoulos, AG; Apidianakis, Y Oncotarget 2015-12-04 1.38 | Dec 11
Immunopathogenesis of IBD: Current State of the Art de Souza, HSP; Fiocchi, C Nat Rev Gastroenterol Hepatol 2015-12-02 1.37 | Dec 4
Glycogen Synthase Kinase 3 in Wnt Signaling Pathway and Cancer Tejeda-Muñoz, N; Robles-Flores, M IUBMB Life 2015-11-24 1.36 | Nov 27
Leukocyte trafficking to the Small Intestine and Colon Habtezion A; Nguyen, LP; Hadeiba, H; Butcher, EC Gastroenterology 2015-11-06 1.35 | Nov 20
Therapeutic Targets in the Wnt Signaling Pathway: Feasibility of Targeting TNIK in Colorectal Cancer Masuda, M; Sawa, M; Yamada, T Pharmacol Ther 2015-11-02 1.34 | Nov 13
Nanomedicine and Drug Delivery Strategies for Treatment of Inflammatory Bowel Disease Takedatsu, H; Mitsuyama, K; Torimura, T World J Gastroenterol 2015-10-28 1.34 | Nov 6
DNA Methylation Dynamics during Differentiation, Proliferation, and Tumorigenesis in the Intestinal Tract Huang, CZ; Yu, T; Chen, QK Stem Cells Dev 2015-10-20 1.31 | Oct 23
Targeting Colorectal Cancer Stem Cells Using Curcumin and Curcumin Analogues: Insights into the Mechanism of the Therapeutic Efficacy Ramasamy, TS; Ayob, AZ; Myint, HHL; Thiagarajah, S; Amini, F Cancer Cell Int 2015-10-09 1.30 | Oct 16
Mini-Gut Organoids: Reconstitution of Stem Cell Niche Date, S; Sato, T Annu Rev Cell Dev Biol 2015-10-02 1.29 | Oct 9
Ghrelin and Motilin Receptors as Drug Targets for Gastrointestinal Disorders Sanger, GJ; Furness, JB Nat Rev Gastroenterol Hepatol 2015-09-22 1.28 | Oct 2
Genetically Engineered Mouse Models for Studying Inflammatory Bowel Disease Mizoguchi, E; Okada, T; Himuro, H; Takeuchi, T; Mizoguchi J Pathol 2015-09-21 1.27 | Sep 25
Role of Type 2 Immunity in Intestinal Inflammation Bamias, G; Cominelli, F Curr Opin Gastroenterol 2015-09-15 1.26 | Sep 18
Emerging Cytokine Networks in Colorectal Cancer West, NR; McCuaig, S; Franchini, F; Powrie, F Nat Rev Immunol 2015-09-11 1.25 | Sep 11
Colorectal Cancer Models for Novel Drug Discovery Golovko, D; Kedrin, D; Yilmaz, ÖH; Roper, J Expert Opin Drug Discov 2015-08-21 1.24 | Sep 4
The Intestinal Epithelium as Guardian of Gut Barrier Integrity Zhang, K; Hornef, MW; Dupont, A Cell Microbiol 2015-08-20 1.23 | Aug 28
New Insights into Immune Mechanisms Underlying Autoimmune Diseases of the Gastrointestinal Tract Di Sabatino, A; Lenti, MV; Giuffrida, P; Vanoli, A; Corazza, GR Autoimmun Rev 2015-08-12 10.22 | Aug 21
Targeting Wnt Signaling in Colorectal Cancer Novellasdemunt, L; Antas, P; Li, VS Am J Physiol Cell Physiol 2015-08-19 10.22 | Aug 21
Understanding Inflammatory Bowel Disease via Immunogenetics de Lange, KM; Barrett, JC J Autoimmun 2015-08-06 1.21 | Aug 14
The TGF-β/Smad System in IBD Pathogenesis Sedda, S; Marafini, I; Dinallo, V; Di Fusco, D; Monteleone, G Inflamm Bowel Dis 2015-07-30 1.20 | Aug 7
Epigenetic Regulation of the Intestinal Epithelium Elliott, EN; Kaestner, KH Cell Mol Life Sci 2015-07-29 1.19 | Jul 31
The Promise of Metabolic Phenotyping in Gastroenterology and Hepatology Holmes, E; Wijeyesekera, A; Taylor-Robinson, SD; Nicholson, JK Nat Rev Gastroenterol Hepatol 2015-07-21 1.18 | Jul 24
Reserve Stem Cells: Differentiated Cells Reprogram to Fuel Repair, Metaplasia, and Neoplasia in the Adult Gastrointestinal Tract Mills, JC; Sansom, OJ Sci Signal 2015-07-14 1.17 | Jul 17
Role of Epithelial Cells in the Pathogenesis and Treatment of Inflammatory Bowel Disease Okamoto, R; Watanabe, M J Gastroenterol 2015-07-03 1.16 | Jul 10
Celiac Disease and Gluten-Related Disorders in Childhood Vriezinga, SL; Schweizer, JJ; Koning, F; Mearin, ML Nat Rev Gastroenterol Hepatol 2015-06-23 1.15 | Jul 3
Stem vs Non-Stem Cell Origin of Colorectal Cancer Huels, DJ; Sansom, OJ Br J Cancer 2015-06-25 1.14 | Jun 26
Tenapanor Hydrochloride for the Treatment of Constipation-Predominant Irritable Bowel Syndrome Zielińska, M; Wasilewski, A; Fichna, J Expert Opin Investig Drugs 2015-06-12 1.13 | Jun 19
All for One and One for All: Regionalization of the Drosophila Intestine Buchon, N; Osman D Insect Biochem Mol Biol 2015-06-01 1.12 | Jun 12
Multiscale Analysis of the Murine Intestine for Modeling Human Diseases Lyons, J; Herring, CA; Banerjee, A; Simmons AJ; Lau, KS Integr Biol 2015-05-22 1.11 | Jun 5
Intestinal Stem Cell Proliferation and Epithelial Homeostasis in the Adult Drosophila Midgut Nászai, M; Carroll, LR; Cordero, JB Insect Biochem Mol Biol 2015-05-26 1.11 | Jun 5
MicroRNAs in Tumorigenesis, Metastasis, Diagnosis and Prognosis of Gastric Cancer Jiang, C: Chen, X; Alattar, M; Wei, J, Liu, H Cancer Gene Ther 2015-05-22 1.11 | Jun 5
Compartmentalizing Intestinal Epithelial Cell Toll-Like Receptors for Immune Surveillance Yu, S; Gao, N Cell Mol Life Sci 2015-05-23 1.10 | May 29
Repairing Organs: Lessons from Intestine and Liver Gehart, H; Clevers, H Trends Genet 2015-05-16 1.09 | May 22
Serrated neoplasia—Role in Colorectal Carcinogenesis and Clinical Implications IJspeert, JEG; Vermeulen, L; Meijer, GA; Dekker, J Nat Rev Gastroenterol Hepatol 2015-05-12 1.08 | May 15
Microenvironmental Control of Stem Cell Fate in Intestinal Homeostasis and Disease Biswas, S; Davis, H; Irshad, S; Sandberg, T; Worthley, D; Leedham, S J Pathol 2015-05-14 1.08 | May 15
Intestinal Barrier Loss as a Critical Pathogenic Link Between Inflammatory Bowel Disease and Graft-Versus-Host Disease Nalle, SC; Turner, JR Mucosal Immunol 2015-05-06 1.07 | May 7
Diverse Roles of LPA Signaling in the Intestinal Epithelium Yun, CC; Kumar, A Exp Cell Res 2015-05-01 1.06 | May 1
Somatic Stem Cell Heterogeneity: Diversity in the Blood, Skin and Intestinal Stem Cell Compartments Goodwell, MA; Nguyen, H; Shroyer, N Nat Rev Mol Cell Biol 2015-04-23 1.05 | Apr 24
Colorectal cancer: Back to the stroma—the real villain in colorectal cancer? Colvin, H; Mori M Nat Rev Gastroenterol Hepatol 2015-04-21 1.05 | Apr 24
New Developments in Goblet Cell Mucus Secretion and Function Birchenough GM, Johansson ME, Gustafsson JK, Bergström JK, Hansson GC Mucosal Immunol 2015-04-15 1.04 | Apr 17
Stem Cell and Progenitor Fate in the Mammalian Intestine: Notch and Lateral Inhibition in Homeostasis and Disease Sancho, R; Cremona, CA; Behrens, A EMBO Rep 2015-04-08 1.03 | Apr 10
Generating Human Intestinal Tissues from Pluripotent Stem Cells to Study Development and Disease Sinagoga, K; Wells, JM EMBO J 2015-03-19 1.02 | Mar 27
Role of the Intestinal Cytokine Microenvironment in Shaping the Intraepithelial Lymphocyte Repertoire Yang, H; Xiao, W; Wang, W; Qiu, Y J Leukocyte Biol 2015-05-12 1.01 | Mar 20
STAT3-Activating Cytokines: A Therapeutic Opportunity for Inflammatory Bowel Disease? Ernst, M; Putoczki,TL; Nguyen, PM J Interf Cytok Res 2015-03-11 1.00 | Mar 13
Intestinal Dendritic Cells O’Mahony, L; Smolinska, S; Schiavi, E Curr Opin Gastroen 2015-03-01 1.00 | Mar 13